This is the second online test of the GPAT preparation test series. Topic included in this is:
a) Glycosides
b) Important name reactioons of organic chemistry
c) Antiviral drugs
d) Tablets
e) Phytochemical screening
a) Glycosides
b) Important name reactioons of organic chemistry
c) Antiviral drugs
d) Tablets
e) Phytochemical screening
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1. Stomata present in the digitallis includes:
a) Anomocytic
b) Anisocytic
c) Paracytic
d) Diacytic
2. Which is a distinguished feature of the trichomes of digitallis?
a) Collapsed cell covering
b) Biseriate trichomes
c) Contains thorns
d) Ca oxalate crystals
a) 2
b) 3
c) 4
d) 5
4. Purpurea glycoside on hydrolysis does not give:
a) Digitoxigenin
b) Gitoxigenin
c) Digoxigenin
d) All of the above
5. Which of the following is an adulterant of digitallis leave?
a) Verbascun Thapsus
b) Primorsa leaves (Primorsa vulgaris)
c) Comfrey leaves (Symphyticum officinale)
d) All of the above
6. Senna leaves have which type of stomata?
a) Anomocytic
b) Anisocytic
c) Paracytic
d) Diacytic
7. Aglycone moiety of sennosides is known as
a) Anthraquinone
b) Anthrone
c) Athraquinolone
d) Rhein dianthrone
8. Which of the following statement is true about anthrone and anthranols?
8. Which of the following statement is true about anthrone and anthranols?
a) Anthrone is pale yellow substance which is not soluble in alkali and also doesn’t give any fluroscence.
b) Anthranols on other hand are soluble in alkali & gives strong fluroscence in alkali.
c) Anthrones and anthranols are differentiated on the basis of fluroscence test.
d) All of the above statements are true for the same.
9. Which of the following reagents is used for studying the misroscopy of aloe powder?
a) Sudan III
b) Cresol red
c) Lactophenol
d) Thymol blue
10. Which constituent is responsible for the purgative action of aloe?
a) Aloin
b) Barabaloin
c) Aloescin
d) None of the above
11. Which of the following tests is used for distinguish between different varieties of aloe?
a) Bromine test
b) Schoententen’s test
c) Klunge’s isobarbaloin test
d) None of the above
12. Which of the following acids is used for the special test for the aloe?
a) Sulfuric acid
b) Nitric acid
c) Hydrochloride
d) Accetic acid
13. The main constituent of aloin is:
a) Barbaloin
b) Aloescin
c) Emodin
d) Sennoside
14. Glycirrhiza glabra belongs to the family:
a) polygonaceae
b) leguminosae
c) rhamnaceae
d) dioscoreace
15. The main feature of the liquorice roots is:
a) Presence of tetrach xylem
b) Presence of stolon
c) Presnence of Ca crystals
d) Presence of starch
16. Chemically, Glycirhizin is which of the terpenoids?
a) Monoterpenoid saponin.
b) Diterpenoid saponin.
c) Triterpenoid saponin.
d) Tetraterpenoid saponin.
17. Chemically, glycirhizin is:
a) Na & K salt of glycirrhizinic acid
b) K & Ca salt of glycirrhizinic acid
c) Mg & Ca salt of glycirrhizinic acid
d) Na & Mg salt of glycirrhizinic acid
18. On hydrolysis, glycirrhizinic acid gives:
a) Glycirhizin
b) Glycirhiza
c) glycirehnizinic acid
d) glycrrhetinic acid
19. Flavonoids present in the liquorice in traces which posses antiulcer and antigastric properties:
a) Glycirhizin
b) Glycirhiza
c) glycrrhetinic acid
d) Liquiritin & Isoliquirin
20. Which of the following acids is used for phytochemical test for the Glycirhizin?
a) Sulfuric acid
b) Nitric acid
c) Hydrochloride
d) Accetic acid
21. Biological source of indian rhubarb is:
a) Rheum Palmatum
b) Rheum emodii
c) Rheum webiannum
d) None of the above
22. Which constituent of rhubarb is responsible for the astringent properties?
a) Rhein
b) Emodin
c) gallic acid
d) rhaponitic
23. Which constituent of the rhubarb is mainly possess estrogenic activity?
a) Rhein
b) Emodin
c) gallic acid
d) rhaponitic
24. Following is an example of C-glycoside:
a) Dioscorea
b) Senna
c) Cascara
d) Digitallis
25. Which is true for the microscopy of the dioscorea?
a) Epidermis is absent.
b) Stele is the major part of the drug.
c) Endodermis & pericycle are indistinguishable.
d) All is true for the dioscorea.
26. Which of the following is used as nucleophile in benzoin condensation?
a) Hydroxyl ion
b) Cyanide ion
c) Alkoxy ion
d) Any of the above nucleophile can be used.
27. Which is true for the cannizaro's reaction?
a) Aldehyde should contain alpha hydrogen.
b) Aldehyde should not contain alpha hydrogen
c) Aldehyde reacts with the corresponding ketone to give desired product.
d) All of the aboe statements are true for the cannizaro's reaction.
28. In aldol condensaion, what is the role of nucleophile used?
a) Nucleophilic substitution
b) Proton abstraction from the aldehyde
c) Condensation
d) Cycloaddition
29. When o-methoxy phenol is reacted with NaOH and chloroform, the product we obtain is:
a) Vanillin
b) Salicylaldehyde
c) Salicylic acid
d) Vanilic acid
30. When carboxylic esters containing an α-hydrogen are treated with a strong base, the product we get is:
a) β-ketoester & an alcohol
b) homologous of carboxylic acid having increased methyl group
c) β-hydroxy ketone and alcohol
d) β-ketoester & β-hydroxy ketone
31. When 2,3 dimethyl butan-2,3diol is reacted with an acid, we get
a) 3,3 dimethyl butan-2-one
b) 3,3 dimethyl butan-2,3-dione
c) 3,4 dimethyl butan-2-one
d) 2,3 dimethyl butan-2-one
32. The main role of the diluents in the tablet formulation is:
a) to impart bulk to the tablet
b) for the purpose of breaking the tablet when introduced in the biological system.
c) to increase the cohesive forces between the ingredients of the tablet so that tablet can be compressed easily.
d) to enhance the flow properties of the granules or powders
33. Which of the following diluents is used in chewable tablets?
a) Microcrystalline cellulose
b) Mannitol
c) α-Lactose
d) CaCO3
34. Which of the following excipient serve the dual purpose of disintegrant and binder?
a) Nymcel
b) Starch
c) Avicel
d) Primogel
35. Which of the following is not an disintegrant?
a) Nymcelb) Starch
c) Avicel
d) Acacia
36. Binder used for Non-aqueous granulation is:
a) Starch
b) PVP
c) Tragacanth
d) Gelatin
37. The main role of the glidants in the tablet formulation is:
a) for the comfortable ejection of the tablet
b) to enhance the flow properties of the granules or powders
c) to increase the cohesive forces between the ingredients of the tablet
d) for the purpose of breaking the tablet when introduced in the biological system
a) Liquid Paraffin
b) Colloidal Silica
c) Talc
d) PVP
39. Covering of the genome of virus by proteinaceous coat is called:
a) Nucleus
b) Capsid
c) Genetic content
d) Cytoplasm
40. Which of the following drugs is used as anti-herpes drug?
a) Acyclovir
b) Amantadine
c) Vidabarine
d) Methisazone
a) Acyclovir
b) Amantadine
c) Vidabarine
d) Methisazone
a) Acyclovir
b) Amantadine
c) Vidabarine
d) Methisazone
a) Thymidyl kinase
b) Thymidyl synthetase
c) DNA transcriptase
d) Reverse transcriptase
44. The main character of amantadine responsible for its mechanism of action is:
a) Strong Acidic nature
b) Weak basic nature
c) Weak acidic nature
d) Strong basic nature
a) Anemia
b) Granulocytopenia
c) Thrombocytopenia
d) All of the above
46. Chemically reagent for the Dragendroff’s reagent is:
a) potassium mercuric iodide
b) potassium bismuth iodide
c) iodine potassium iodide
d) picric acid
47. Chemically reagent for the Mayer’s reagent is:
a) potassium mercuric iodide
b) potassium bismuth iodide
c) iodine potassium iodide
d) picric acid
48. Chemically reagent for the Wagner’s reagent is:
a) potassium mercuric iodide
b) potassium bismuth iodide
c) iodine potassium iodide
d) picric acid
49. Chemically reagent for the Hager’s reagent is:
a) potassium mercuric iodide
b) potassium bismuth iodide
c) iodine potassium iodide
d) picric acid
50. Which of the following test is used for the phytochemical screening of anthraquinone glycosides?
a) Brontrager's test
b) Kedde's test
c) Baljet test
d) Salwoski test
51. Brontrager's test is done for:
a) O-glycosides
b) C-glycosides
c) N-glycosides
d) S-glycosides
52. Modified brontrager’s test is done for:
a) O-glycosides
b) C-glycosides
c) N-glycosides
d) S-glycosides
53. Which of the following is done for the phyochemical screening of cardiac glycosides?
a) Keller-Killiani test
b) Kedde's test
c) Baljet test
d) All of the above
54. Test responsible for the digitoxose sugar moiety in cardiac glycosides is:
a) Keller-Killiani test
b) Kedde's test
c) Baljet test
d) All of the above
55. Reagent of Raymond's test is:
a) pyridine
b) sodium nitroprusside
c) methanolic alkali.
d) Picric acid
56. Reagent of Baljet test is:
a) pyridine
b) sodium nitroprusside
c) methanolic alkali.
d) Picric acid
57. Reagent of Legal's test is:
a) pyridine & alkaline sodium nitroprusside
b) sodium nitroprusside
c) methanolic alkali.
d) Picric acid
58. Which of the following chemical test is used for detecting terpenoids and steroids in the plants?
a) Brontrager's test
b) Kedde's test
c) Baljet test
d) Salwoski test
59. Shinoda test is used for the screening of:
a) Tannins
b) Flavonoids
c) Alkaloids
d) Terpenoids
60. Liberman-Burchard test is used for the phytochemical screening of:
a) Tannins
b) Flavonoids
c) Alkaloids
d) Terpenoids
61. Shinoda test is performed by using the following reagent:
a) Mg & HCL
b) K & HCL
c) Mn & HCL
d) Mn & H2SO4
62. Acid used for the salwoski test is:
a) Sulfuric acid
b) Nitric acid
c) Hydrochloric acid
d) Accetic acid
63. Tincture alkane is used for the detection of:
a) Tannins
b) Volatile oils
c) Flavonoids
d) Terpenoids
64. Alcoholic solution of sudan III is used for the phytochemical screening of:
a) Tannins
b) Volatile oils
c) Flavonoids
d) Terpenoids
65. Gold beater’s skin test is used for testing of:
a) Tannins
b) Volatile oils
c) Flavonoids
d) Terpenoids
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