Objective questions for GPAT preparation: Series II

This is the second online test of the GPAT preparation test series. Topic included in this is:

a) Glycosides
b) Important name reactioons of organic chemistry
c) Antiviral drugs
d) Tablets
e) Phytochemical screening

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1. Stomata present in the digitallis includes:

a) Anomocytic

b) Anisocytic

c) Paracytic

d) Diacytic

2. Which is a distinguished feature of the trichomes of digitallis?

a) Collapsed cell covering

b) Biseriate trichomes

c) Contains thorns

d) Ca oxalate crystals

3. On hydrolysis purpurea glycoside A & B gives how many molecules of digitoxose and gitoxose respectively?

a) 2

b) 3

c) 4

d) 5

4. Purpurea glycoside on hydrolysis does not give:

a) Digitoxigenin

b) Gitoxigenin

c) Digoxigenin

d) All of the above

5. Which of the following is an adulterant of digitallis leave?

a) Verbascun Thapsus

b) Primorsa leaves (Primorsa vulgaris)

c) Comfrey leaves (Symphyticum officinale)

d) All of the above

6. Senna leaves have which type of stomata?

a) Anomocytic

b) Anisocytic

c) Paracytic

d) Diacytic

7. Aglycone moiety of sennosides is known as

a) Anthraquinone

b) Anthrone

c) Athraquinolone

d) Rhein dianthrone

8. Which of the following statement is true about anthrone and anthranols?

a) Anthrone is pale yellow substance which is not soluble in alkali and also doesn’t give any fluroscence.

b) Anthranols on other hand are soluble in alkali & gives strong fluroscence in alkali.

c) Anthrones and anthranols are differentiated on the basis of fluroscence test.

d) All of the above statements are true for the same.

9. Which of the following reagents is used for studying the misroscopy of aloe powder?

a) Sudan III

b) Cresol red

c) Lactophenol

d) Thymol blue

10. Which constituent is responsible for the purgative action of aloe?

a) Aloin

b) Barabaloin

c) Aloescin

d) None of the above

11. Which of the following tests is used for distinguish between different varieties of aloe?

a) Bromine test

b) Schoententen’s test

c) Klunge’s isobarbaloin test

d) None of the above

12. Which of the following acids is used for the special test for the aloe?

a) Sulfuric acid

b) Nitric acid

c) Hydrochloride

d) Accetic acid

13. The main constituent of aloin is:

a) Barbaloin

b) Aloescin

c) Emodin

d) Sennoside

14. Glycirrhiza glabra belongs to the family:

a) polygonaceae

b) leguminosae

c) rhamnaceae

d) dioscoreace

15. The main feature of the liquorice roots is:

a) Presence of tetrach xylem

b) Presence of stolon

c) Presnence of Ca crystals

d) Presence of starch

16. Chemically, Glycirhizin is which of the terpenoids?

a) Monoterpenoid saponin.

b) Diterpenoid saponin.

c) Triterpenoid saponin.

d) Tetraterpenoid saponin.

17. Chemically, glycirhizin is:

a) Na & K salt of glycirrhizinic acid

b) K & Ca salt of glycirrhizinic acid

c) Mg & Ca salt of glycirrhizinic acid

d) Na & Mg salt of glycirrhizinic acid

18. On hydrolysis, glycirrhizinic acid gives:

a) Glycirhizin

b) Glycirhiza

c) glycirehnizinic acid

d) glycrrhetinic acid

19. Flavonoids present in the liquorice in traces which posses antiulcer and antigastric properties:

a) Glycirhizin

b) Glycirhiza

c) glycrrhetinic acid

d) Liquiritin & Isoliquirin

20. Which of the following acids is used for phytochemical test for the Glycirhizin?

a) Sulfuric acid

b) Nitric acid

c) Hydrochloride

d) Accetic acid

21. Biological source of indian rhubarb is:

a) Rheum Palmatum

b) Rheum emodii

c) Rheum webiannum

d) None of the above

22. Which constituent of rhubarb is responsible for the astringent properties?

a) Rhein

b) Emodin

c) gallic acid

d) rhaponitic

23. Which constituent of the rhubarb is mainly possess estrogenic activity?

a) Rhein

b) Emodin

c) gallic acid

d) rhaponitic

24. Following is an example of C-glycoside:

a) Dioscorea

b) Senna 

c) Cascara

d) Digitallis

25. Which is true for the microscopy of the dioscorea?

a) Epidermis is absent.

b) Stele is the major part of the drug.

c) Endodermis & pericycle are indistinguishable.

d) All is true for the dioscorea.

26. Which of the following is used as nucleophile in benzoin condensation?

a) Hydroxyl ion

b) Cyanide ion

c) Alkoxy ion

d) Any of the above nucleophile can be used.

27. Which is true for the cannizaro's reaction?

a) Aldehyde should contain alpha hydrogen.

b) Aldehyde should not contain alpha hydrogen

c) Aldehyde reacts with the corresponding ketone to give desired product.

d) All of the aboe statements are true for the cannizaro's reaction.

28. In aldol condensaion, what is the role of nucleophile used?

a) Nucleophilic substitution

b) Proton abstraction from the aldehyde

c) Condensation

d) Cycloaddition

29.  When o-methoxy phenol is reacted with NaOH and chloroform, the product we obtain is:

a) Vanillin

b) Salicylaldehyde

c) Salicylic acid

d) Vanilic acid

30. When carboxylic esters containing an α-hydrogen are treated with a strong base, the product we get is:

a) β-ketoester & an alcohol

b) homologous of carboxylic acid having increased methyl group

c) β-hydroxy ketone and alcohol

d) β-ketoester & β-hydroxy ketone

31. When 2,3 dimethyl butan-2,3diol is reacted with an acid, we get

a) 3,3 dimethyl butan-2-one

b) 3,3 dimethyl butan-2,3-dione

c) 3,4 dimethyl butan-2-one

d) 2,3 dimethyl butan-2-one

32. The main role of the diluents in the tablet formulation is:

a) to impart bulk to the tablet

b) for the purpose of breaking the tablet when introduced in the biological system.

c) to increase the cohesive forces between the ingredients of the tablet so that tablet can be compressed easily.

d) to enhance the flow properties of the granules or powders 

33. Which of the following diluents is used in chewable tablets?

a) Microcrystalline cellulose

b) Mannitol

c) α-Lactose

d) CaCO3

34. Which of the following excipient serve the dual purpose of disintegrant and binder?

a) Nymcel

b) Starch

c) Avicel

d) Primogel

35. Which of the following is not an disintegrant?

a) Nymcel
b) Starch
c) Avicel
d) Acacia

36. Binder used for Non-aqueous granulation is:
a) Starch
b) PVP
c) Tragacanth
d) Gelatin 

37. The main role of the glidants in the tablet formulation is:
a) for the comfortable ejection of the tablet
b) to enhance the flow properties of the granules or powders
c) to increase the cohesive forces between the ingredients of the tablet
d) for the purpose of breaking the tablet when introduced in the biological system

38. Which of the following is a lubricant in the tablet formulation?
a) Liquid Paraffin
b) Colloidal Silica
c) Talc
d) PVP

39. Covering of the genome of virus by proteinaceous coat is called:
a) Nucleus
b) Capsid
c) Genetic content
d) Cytoplasm

40. Which of the following drugs is used as anti-herpes drug?
a) Acyclovir
b) Amantadine
c) Vidabarine
d) Methisazone

41.  Which of the following drugs is used as anti-influenza drug?
a) Acyclovir
b) Amantadine
c) Vidabarine
d) Methisazone

42. Which of the following drugs is used as anti-small pox drug?
a) Acyclovir
b) Amantadine
c) Vidabarine
d) Methisazone

43. The main target for the acyclovir is:
a) Thymidyl kinase
b) Thymidyl synthetase
c) DNA transcriptase
d) Reverse transcriptase

44. The main character of amantadine responsible for its mechanism of action is:
a) Strong Acidic nature
b) Weak basic nature
c) Weak acidic nature
d) Strong basic nature

45. Which of the following is the adverse affect of anti-HIV drugs?
a) Anemia

b) Granulocytopenia

c) Thrombocytopenia

d) All of the above

46. Chemically reagent for the Dragendroff’s reagent is:

a) potassium mercuric iodide

b) potassium bismuth iodide

c) iodine potassium iodide

d) picric acid

47. Chemically reagent for the Mayer’s reagent is:

a) potassium mercuric iodide

b) potassium bismuth iodide

c) iodine potassium iodide

d) picric acid

48. Chemically reagent for the Wagner’s reagent is:

a) potassium mercuric iodide

b) potassium bismuth iodide

c) iodine potassium iodide

d) picric acid

49. Chemically reagent for the Hager’s reagent is:

a) potassium mercuric iodide

b) potassium bismuth iodide

c) iodine potassium iodide

d) picric acid

50. Which of the following test is used for the phytochemical screening of anthraquinone glycosides?

a) Brontrager's test

b) Kedde's test 

c) Baljet test

d) Salwoski test

51. Brontrager's test is done for:

a) O-glycosides

b) C-glycosides

c) N-glycosides

d) S-glycosides

52. Modified brontrager’s test is done for:

a) O-glycosides

b) C-glycosides

c) N-glycosides

d) S-glycosides

53. Which of the following is done for the phyochemical screening of cardiac glycosides?

a) Keller-Killiani test

b) Kedde's test 

c) Baljet test

d) All of the above

54. Test responsible for the digitoxose sugar moiety in cardiac glycosides is:

a) Keller-Killiani test

b) Kedde's test 

c) Baljet test

d) All of the above

55. Reagent of Raymond's test is:

a) pyridine 

b) sodium nitroprusside 

c) methanolic alkali.

d) Picric acid

56. Reagent of Baljet test is:

a) pyridine 

b) sodium nitroprusside 

c) methanolic alkali.

d) Picric acid

57. Reagent of Legal's test is:

a) pyridine & alkaline sodium nitroprusside

b) sodium nitroprusside 

c) methanolic alkali.

d) Picric acid

58. Which of the following chemical test is used for detecting terpenoids and steroids in the plants?

a) Brontrager's test

b) Kedde's test 

c) Baljet test

d) Salwoski test

59. Shinoda test is used for the screening of:

a) Tannins 

b) Flavonoids

c) Alkaloids

d) Terpenoids

60. Liberman-Burchard test is used for the phytochemical screening of:

a) Tannins 

b) Flavonoids

c) Alkaloids

d) Terpenoids

61. Shinoda test is performed by using the following reagent:

a) Mg & HCL

b) K & HCL

c) Mn & HCL

d) Mn & H2SO4

62. Acid used for the salwoski test is:

a) Sulfuric acid

b) Nitric acid

c) Hydrochloric acid

d) Accetic acid

63. Tincture alkane is used for the detection of:

a) Tannins

b) Volatile oils

c) Flavonoids

d) Terpenoids

64. Alcoholic solution of sudan III is used for the phytochemical screening of:

a) Tannins

b) Volatile oils

c) Flavonoids

d) Terpenoids

65. Gold beater’s skin test is used for testing of:

a) Tannins

b) Volatile oils

c) Flavonoids

d) Terpenoids

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